Version 5.4
Mus musculus Gene: Ttyh3
Summary
InnateDB Gene IDBG-206981.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttyh3
Gene Name tweety homolog 3 (Drosophila)
Synonyms 2900029G13Rik; AI414930
Species Mus musculus
Ensembl Gene ENSMUSG00000036565
Encoded Proteins
IDBP-206983
tweety homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136295:
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:140620586-140649031
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000042661 ENSMUSP00000037447
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005254 chloride channel activity
Biological Process
GO:0006821 chloride transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136295
View Gene Order
ENSBTAG00000005934
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_268398
Orphan transporters pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6P5F7
TrEMBL
UniProt Splice Variant
Entrez Gene 78339
UniGene Mm.28947
RefSeq NM_175274 XM_006504770
OMIM
CCDS CCDS19822
HPRD
IMGT
MGI ID MGI:1925589
MGI Symbol Ttyh3
EMBL AK052340 AK173233 BC059083 BC062917
GenPept AAH59083 AAH62917 BAC34944 BAD32511
RNA Seq Atlas 78339

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca