Version 5.4
Mus musculus Gene: Spg11
Summary
InnateDB Gene IDBG-202655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spg11
Gene Name spastic paraplegia 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033396
Encoded Proteins
IDBP-202657
spastic paraplegia 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104133:
The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:122053520-122118386
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000036450 ENSMUSP00000037543
ENSMUST00000133145
ENSMUST00000135847
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104133
View Gene Order
ENSBTAG00000000362
Not yet available
Cross-References
SwissProt Q3UHA3
TrEMBL
UniProt Splice Variant
Entrez Gene 214585
UniGene Mm.222303 Mm.487631
RefSeq NM_145531 XM_006499108 XM_006499109
OMIM
CCDS CCDS50687
HPRD
IMGT
MGI ID MGI:2444989
MGI Symbol Spg11
EMBL AK039286 AK049236 AK049617 AK083468 AK129453 AK147500 AL845457 BC019404
GenPept AAH19404 BAC30307 BAC33628 BAC33842 BAC38926 BAC98263 BAE27954 CAM21781
RNA Seq Atlas 214585

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca