Version 5.4
Bos taurus Gene: SPG11
Summary
InnateDB Gene IDBG-646934.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPG11
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000362
Encoded Proteins
IDBP-699787
spastic paraplegia 11 (autosomal recessive)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104133:
The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:104004263-104081363
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000470 ENSBTAP00000000470
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104133
View Gene Order
ENSMUSG00000033396
View Gene Order
Cross-References
SwissProt
TrEMBL F1MEB4
UniProt Splice Variant
Entrez Gene 507819
UniGene Bt.105261
RefSeq XM_002691092 XM_864766
HUGO HGNC:11226
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02030047 DAAA02030048 DAAA02030049 DAAA02030050
GenPept
RNA Seq Atlas 507819

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca