Version 5.4
Mus musculus Protein: Spg11
Summary
InnateDB Protein IDBP-202657.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spg11
Protein Name spastic paraplegia 11
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037543
InnateDB Gene IDBG-202655 (Spg11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, cytosol. Nucleus. Note=Mainly cytoplasmic. {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed at low level. {ECO:0000269PubMed:17322883}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2444989
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UHA3
PhosphoSite PhosphoSite-Q3UHA3
TrEMBL
UniProt Splice Variant
Entrez Gene 214585
UniGene Mm.487631
RefSeq NP_663506
MGI ID
MGI Symbol Spg11
OMIM
CCDS CCDS50687
HPRD
IMGT
EMBL AK039286 AK049236 AK049617 AK083468 AK129453 AK147500 AL845457 BC019404
GenPept AAH19404 BAC30307 BAC33628 BAC33842 BAC38926 BAC98263 BAE27954 CAM21781

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca