InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC22A8

Summary

InnateDB Protein

IDBP-585633.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC22A8

Protein Name

solute carrier family 22 (organic anion transporter), member 8

Synonyms

OAT3;

Species

Homo sapiens

Ensembl Protein

ENSP00000441658

InnateDB Gene

IDBG-52313 (SLC22A8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005452	inorganic anion exchanger activity
GO:0022857	transmembrane transporter activity

Biological Process

GO:0009636	response to toxic substance
GO:0034220	ion transmembrane transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF00083
PF07690

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8TCC7

PhosphoSite

PhosphoSite-Q8TCC7

TrEMBL

UniProt Splice Variant

Entrez Gene

9376

UniGene

Hs.266223

RefSeq

NP_001171662

HUGO

HGNC:10972

OMIM

607581

CCDS

CCDS53644

HPRD

IMGT

EMBL

AB042505 AB209692 AF097491 AK298341 AP001858 BC022387

GenPept

AAD19357 AAH22387 BAB47393 BAD92929 BAG60589