Version 5.4
Homo sapiens Protein: ZNF185
Summary
InnateDB Protein IDBP-382631.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF185
Protein Name zinc finger protein 185 (LIM domain)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000395228
InnateDB Gene IDBG-89312 (ZNF185)
Protein Structure
UniProt Annotation
Function May be involved in the regulation of cellular proliferation and/or differentiation.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000269PubMed:16799630}. Cell junction, focal adhesion {ECO:0000269PubMed:16799630}.
Disease Associations
Tissue Specificity Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
PFAM PF00412
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15231
PhosphoSite PhosphoSite-O15231
TrEMBL B3KPM4
UniProt Splice Variant
Entrez Gene 7739
UniGene Hs.718294
RefSeq NP_001171579
HUGO HGNC:12976
OMIM 300381
CCDS CCDS55528
HPRD 02306
IMGT
EMBL AK056517 AK095258 AK296967 AK301530 AY997296 CH471172 DQ508022 DQ508023 DQ508024 DQ508025 DQ508026 U82671 Y09538
GenPept AAY54245 ABF57657 ABF57658 ABF57659 ABF57660 ABF57661 BAC04511 BAG51736 BAG59511 BAH13507 CAA70733 EAW72893 EAW72895

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca