Version 5.4
Homo sapiens Gene: ZNF185
Summary
InnateDB Gene IDBG-89312.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF185
Gene Name zinc finger protein 185 (LIM domain)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147394
Encoded Proteins
IDBP-89314
zinc finger protein 185 (LIM domain)
IDBP-89316
zinc finger protein 185 (LIM domain)
IDBP-89318
zinc finger protein 185 (LIM domain)
IDBP-89320
zinc finger protein 185 (LIM domain)
IDBP-89322
zinc finger protein 185 (LIM domain)
IDBP-382631
zinc finger protein 185 (LIM domain)
IDBP-382641
zinc finger protein 185 (LIM domain)
IDBP-382646
zinc finger protein 185 (LIM domain)
IDBP-382649
zinc finger protein 185 (LIM domain)
IDBP-382651
zinc finger protein 185 (LIM domain)
IDBP-589453
zinc finger protein 185 (LIM domain)
IDBP-594857
zinc finger protein 185 (LIM domain)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:152914442-152973480
Strand Forward strand
Band q28
Transcripts
ENST00000370270 ENSP00000359293
ENST00000324823 ENSP00000325307
ENST00000370268 ENSP00000359291
ENST00000318529 ENSP00000313919
ENST00000318504 ENSP00000312782
ENST00000449285 ENSP00000395228
ENST00000426821 ENSP00000409121
ENST00000447792 ENSP00000401766
ENST00000436731 ENSP00000391272
ENST00000454925 ENSP00000392984
ENST00000535861 ENSP00000440847
ENST00000539731 ENSP00000444367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031351
View Gene Order
ENSBTAG00000005776
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.16622 Hs.718294
RefSeq NM_001178106 NM_001178107 NM_001178108 NM_001178109 NM_001178110 NM_001178113 NM_001178115 NM_007150 XM_005274730 XM_005274731 XM_005274733 XM_005274735 XM_005274737 XM_005274738 XM_005274744 XM_005274745 XM_005274746 XM_006724843
HUGO
OMIM
CCDS CCDS48184 CCDS55528 CCDS55529 CCDS55530 CCDS55531 CCDS55532 CCDS69832
HPRD 02306
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca