InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnk1

Summary

InnateDB Protein

IDBP-264129.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Tnk1

Protein Name

tyrosine kinase, non-receptor, 1

Synonyms

Kos1; Tnk1a; Tnk1b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104268

InnateDB Gene

IDBG-192267 (Tnk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0046777	protein autophosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1930958

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR009060 UBA-like
IPR011009 Protein kinase-like domain
IPR013761 Sterile alpha motif/pointed domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF00018
PF14604

PRINTS

PR00109
PR00452

PIRSF

SMART

SM00326
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5F2B4

UniProt Splice Variant

Entrez Gene

83813

UniGene

Mm.358793

RefSeq

MGI ID

MGI Symbol

Tnk1

OMIM

CCDS

HPRD

IMGT

EMBL

AL603707 AL845465

GenPept