Version 5.4
Bos taurus Gene: NPNT
Summary
InnateDB Gene IDBG-640632.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPNT
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006686
Encoded Proteins
IDBP-692932
nephronectin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168743:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:20450525-20529959
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029948 ENSBTAP00000029938
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0007160 cell-matrix adhesion
GO:0010694 positive regulation of alkaline phosphatase activity
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030198 extracellular matrix organization
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033631 cell-cell adhesion mediated by integrin
GO:0045184 establishment of protein localization
GO:0045669 positive regulation of osteoblast differentiation
GO:0045987 positive regulation of smooth muscle contraction
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071356 cellular response to tumor necrosis factor
GO:0097195 pilomotor reflex
GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0016020 membrane
GO:0030485 smooth muscle contractile fiber
GO:0031012 extracellular matrix
GO:0034678 alpha8-beta1 integrin complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000168743
View Gene Order
ENSMUSG00000040998
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
mmu04512
ECM-receptor interaction pathway
INOH
PID NCI
integrin1_pathway
Beta1 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL E1BBK6
UniProt Splice Variant
Entrez Gene 513362
UniGene
RefSeq
HUGO HGNC:27405
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02016663
GenPept
RNA Seq Atlas 513362

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca