InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: TEAD2

Summary

InnateDB Gene

IDBG-62529.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TEAD2

Gene Name

TEA domain family member 2

Synonyms

ETF; TEAD-2; TEF-4; TEF4

Species

Homo sapiens

Ensembl Gene

ENSG00000074219

Encoded Proteins

IDBP-62531

TEA domain family member 2

IDBP-62533

TEA domain family member 2

IDBP-594563

TEA domain family member 2

IDBP-760655

IDBP-764956

IDBP-764254

IDBP-760628

IDBP-764853

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:49340595-49362457

Strand

Reverse strand

Band

q13.33

Transcripts

ENST00000311227	ENSP00000310701
ENST00000377214	ENSP00000366419
ENST00000539846	ENSP00000437928
ENST00000596757	ENSP00000472397
ENST00000593945	ENSP00000469640
ENST00000598823	ENSP00000471743
ENST00000595233
ENST00000601519	ENSP00000469672
ENST00000598810	ENSP00000472109
ENST00000598397

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0001570	vasculogenesis
GO:0001843	neural tube closure
GO:0003143	embryonic heart tube morphogenesis
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0010467	gene expression
GO:0030903	notochord development
GO:0035329	hippo signaling
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048339	paraxial mesoderm development
GO:0048368	lateral mesoderm development
GO:0060548	negative regulation of cell death

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005667	transcription factor complex

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000030796

View Gene Order

ENSBTAG00000016349

Not yet available

Pathways

NETPATH

REACTOME

REACT_116145

PPARA activates gene expression pathway

REACT_19241

Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway

REACT_22279

Fatty acid, triacylglycerol, and ketone body metabolism pathway

REACT_118713

YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway

REACT_12627

Generic Transcription Pathway pathway

REACT_22258

Metabolism of lipids and lipoproteins pathway

REACT_111217

Metabolism pathway

REACT_71

Gene Expression pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.515534 Hs.733534

RefSeq

NM_001256658 NM_001256659 NM_001256660 NM_001256661 NM_001256662 NM_003598 XM_006723423 XM_006723424 XM_006723425 XM_006723426 XM_006723429

HUGO

OMIM

CCDS

CCDS12761 CCDS58670 CCDS58671 CCDS59406

HPRD

IMGT

EMBL

GenPept

RNA Seq Atlas