Version 5.4
Mus musculus Gene: Tead2
Summary
InnateDB Gene IDBG-182196.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tead2
Gene Name TEA domain family member 2
Synonyms Etdf; ETF; TEAD-2; TEF-4; TEF4
Species Mus musculus
Ensembl Gene ENSMUSG00000030796
Encoded Proteins
IDBP-182198
TEA domain family member 2
IDBP-265914
TEA domain family member 2
IDBP-265913
TEA domain family member 2
IDBP-542612
TEA domain family member 2
IDBP-541417
TEA domain family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074219:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45215753-45233635
Strand Forward strand
Band B3
Transcripts
ENSMUST00000033060 ENSMUSP00000033060
ENSMUST00000097216 ENSMUSP00000103430
ENSMUST00000107801 ENSMUSP00000103431
ENSMUST00000138252
ENSMUST00000133835
ENSMUST00000155313 ENSMUSP00000119020
ENSMUST00000134420 ENSMUSP00000117060
ENSMUST00000137094
ENSMUST00000149503
ENSMUST00000139009
ENSMUST00000123130
ENSMUST00000143734
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0001570 vasculogenesis
GO:0001843 neural tube closure
GO:0003143 embryonic heart tube morphogenesis
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0030903 notochord development
GO:0035329 hippo signaling
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048339 paraxial mesoderm development
GO:0048368 lateral mesoderm development
GO:0060548 negative regulation of cell death
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000074219
View Gene Order
ENSBTAG00000016349
Not yet available
Pathways
NETPATH
REACTOME
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_233572
Gene Expression pathway
REACT_198602
PPARA activates gene expression pathway
REACT_196516
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
REACT_206529
Generic Transcription Pathway pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_118713
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
REACT_12627
Generic Transcription Pathway pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3019
RefSeq NM_001285498 NM_001285500 NM_011565 XM_006540776 XM_006540777
OMIM
CCDS CCDS21236 CCDS71957
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca