Version 5.4
Homo sapiens Gene: ANO10
Summary
InnateDB Gene IDBG-28403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANO10
Gene Name anoctamin 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160746
Encoded Proteins
IDBP-28405
anoctamin 10
IDBP-28407
anoctamin 10
IDBP-238222
anoctamin 10
IDBP-373823
anoctamin 10
IDBP-373825
anoctamin 10
IDBP-373828
anoctamin 10
IDBP-373832
anoctamin 10
IDBP-373834
anoctamin 10
IDBP-373835
anoctamin 10
IDBP-373840
anoctamin 10
IDBP-373844
anoctamin 10
IDBP-373846
anoctamin 10
IDBP-373849
anoctamin 10
IDBP-373852
anoctamin 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels. Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:43354859-43691594
Strand Reverse strand
Band p21.33
Transcripts
ENST00000292246 ENSP00000292246
ENST00000350459 ENSP00000327767
ENST00000396091 ENSP00000379398
ENST00000414522 ENSP00000396990
ENST00000451430 ENSP00000394119
ENST00000448045 ENSP00000412997
ENST00000427171 ENSP00000406432
ENST00000428472 ENSP00000416266
ENST00000444344 ENSP00000402010
ENST00000456438 ENSP00000402845
ENST00000413397 ENSP00000399103
ENST00000439141 ENSP00000397360
ENST00000428831 ENSP00000406712
ENST00000436073 ENSP00000404988
ENST00000466658
ENST00000486959
ENST00000495772
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005227 calcium activated cation channel activity
GO:0005229 intracellular calcium activated chloride channel activity
Biological Process
GO:0006812 cation transport
GO:0006821 chloride transport
GO:0008219 cell death
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037949
View Gene Order
ENSBTAG00000008893
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 55129
UniGene Hs.627207 Hs.656657 Hs.738946
RefSeq NM_001204831 NM_001204832 NM_001204833 NM_001204834 NM_018075
HUGO HGNC:25519
OMIM 613726
CCDS CCDS2710 CCDS56247 CCDS56248 CCDS56249 CCDS56250
HPRD 07667
IMGT
EMBL
GenPept
RNA Seq Atlas 55129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca