Version 5.4
Mus musculus Gene: Sergef
Summary
InnateDB Gene IDBG-186121.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sergef
Gene Name secretion regulating guanine nucleotide exchange factor
Synonyms DelGEF; Gef; Gnef; Gnefr
Species Mus musculus
Ensembl Gene ENSMUSG00000030839
Encoded Proteins
IDBP-186123
secretion regulating guanine nucleotide exchange factor
IDBP-542815
secretion regulating guanine nucleotide exchange factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129158:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:46443168-46639807
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000033127 ENSMUSP00000033127
ENSMUST00000156147
ENSMUST00000124962
ENSMUST00000125825
ENSMUST00000135035 ENSMUSP00000116461
ENSMUST00000137988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005087 Ran guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032316 regulation of Ran GTPase activity
GO:0050709 negative regulation of protein secretion
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129158
View Gene Order
ENSBTAG00000005340
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.76659
RefSeq NM_013789 XM_006540943 XM_006540944
OMIM
CCDS CCDS21279
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca