Version 5.4
Homo sapiens Gene: SYT11
Summary
InnateDB Gene IDBG-103318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYT11
Gene Name synaptotagmin XI
Synonyms SYT12; sytXI
Species Homo sapiens
Ensembl Gene ENSG00000132718
Encoded Proteins
IDBP-103320
synaptotagmin XI
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:155859509-155885199
Strand Forward strand
Band q22
Transcripts
ENST00000368324 ENSP00000357307
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0008021 synaptic vesicle
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000068923
View Gene Order
ENSBTAG00000011209
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.32984 Hs.627498
RefSeq NM_152280 XM_005245014
HUGO
OMIM
CCDS CCDS1122
HPRD 12289
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca