InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Birc6

Summary

InnateDB Protein

IDBP-790493.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Birc6

Protein Name

baculoviral IAP repeat-containing 6

Synonyms

A430032G04Rik; A430040A19Rik; AA501170; Bruce; D630005A10Rik; mKIAA1289;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138333

InnateDB Gene

IDBG-197962 (Birc6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0004869	cysteine-type endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0001890	placenta development
GO:0006464	cellular protein modification process
GO:0006915	apoptotic process
GO:0007067	mitotic nuclear division
GO:0008284	positive regulation of cell proliferation
GO:0010951	negative regulation of endopeptidase activity
GO:0015031	protein transport
GO:0016567	protein ubiquitination
GO:0032465	regulation of cytokinesis
GO:0042127	regulation of cell proliferation
GO:0043066	negative regulation of apoptotic process
GO:0060711	labyrinthine layer development
GO:0060712	spongiotrophoblast layer development
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0000922	spindle pole
GO:0005768	endosome
GO:0005802	trans-Golgi network
GO:0005815	microtubule organizing center
GO:0016020	membrane
GO:0030496	midbody

Protein Structure and Domains

PDB ID

MGI:1276108

InterPro

IPR000608 Ubiquitin-conjugating enzyme, E2
IPR001370 Baculoviral inhibition of apoptosis protein repeat
IPR008883 Ubiquitin E2 variant, N-terminal
IPR008979 Galactose-binding domain-like
IPR009079 Four-helical cytokine-like, core
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR017986 WD40-repeat-containing domain
IPR022103 Baculoviral IAP repeat-containing protein 6

PFAM

PF00179
PF00653
PF05743
PF12356

PRINTS

PIRSF

SMART

SM00238

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O88738