InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GIT1

Summary

InnateDB Protein

IDBP-758647.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GIT1

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000464388

InnateDB Gene

IDBG-38394 (GIT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 82 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	82 [view]
Protein-Protein	82 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding

Biological Process

GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005737	cytoplasm
GO:0005925	focal adhesion
GO:0016235	aggresome

Protein Structure and Domains

PDB ID

InterPro

IPR001164 Arf GTPase activating protein
IPR002110 Ankyrin repeat
IPR013724 Spa2 homology (SHD) of GIT
IPR020683 Ankyrin repeat-containing domain
IPR022018 G protein-coupled receptor kinase-interacting protein 1 C term

PFAM