InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cpeb3

Summary

InnateDB Protein

IDBP-534246.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cpeb3

Protein Name

cytoplasmic polyadenylation element binding protein 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118723

InnateDB Gene

IDBG-161232 (Cpeb3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Highly expressed in brain and heart, less in liver, kidney, embryo, skeletal muscle, lung and ovary. Weakly expressed in granular cells of dentate gyrus and the pyramidal cells of CA3 and CA1 of the hippocampus. {ECO:0000269PubMed:12871996}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000900	translation repressor activity, nucleic acid binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003730	mRNA 3'-UTR binding
GO:0005515	protein binding
GO:0008135	translation factor activity, nucleic acid binding
GO:0035613	RNA stem-loop binding
GO:0035925	mRNA 3'-UTR AU-rich region binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006412	translation
GO:0007616	long-term memory
GO:0017148	negative regulation of translation
GO:0045727	positive regulation of translation
GO:0048167	regulation of synaptic plasticity
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060998	regulation of dendritic spine development
GO:0060999	positive regulation of dendritic spine development
GO:0061158	3'-UTR-mediated mRNA destabilization
GO:0071230	cellular response to amino acid stimulus
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:1900248	negative regulation of cytoplasmic translational elongation
GO:1900365	positive regulation of mRNA polyadenylation