Version 5.4
Mus musculus Protein: Tnnt1
Summary
InnateDB Protein IDBP-264219.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnnt1
Protein Name troponin T1, skeletal, slow
Synonyms AW146156; ssTnT; sTnT; Tnt;
Species Mus musculus
Ensembl Protein ENSMUSP00000104228
InnateDB Gene IDBG-138027 (Tnnt1)
Protein Structure
UniProt Annotation
Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in adult soleus muscle. {ECO:0000269PubMed:9651500}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005523 tropomyosin binding
GO:0031014 troponin T binding
Biological Process
GO:0006937 regulation of muscle contraction
GO:0031444 slow-twitch skeletal muscle fiber contraction
GO:0045932 negative regulation of muscle contraction
Cellular Component
GO:0005861 troponin complex
Protein Structure and Domains
PDB ID MGI:1333868
InterPro IPR001978 Troponin
PFAM PF00992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88346
PhosphoSite PhosphoSite-O88346
TrEMBL Q9CTJ8
UniProt Splice Variant
Entrez Gene 21955
UniGene
RefSeq NP_001264832
MGI ID
MGI Symbol Tnnt1
OMIM
CCDS CCDS71880
HPRD
IMGT
EMBL AC161218 AF020946 AJ131711 AK003317 BC141142 BC145450 BC145451 U92882 U92883 U92884
GenPept AAC32540 AAC32541 AAC32546 AAD00730 AAI41143 AAI45451 AAI45452 BAB22711 CAB38082

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca