Mus musculus Gene: Tnnt1
Summary
InnateDB Gene IDBG-138027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnnt1
Gene Name troponin T1, skeletal, slow
Synonyms AW146156; ssTnT; sTnT; Tnt
Species Mus musculus
Ensembl Gene ENSMUSG00000064179
Encoded Proteins
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
troponin T1, skeletal, slow
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the slow skeletal tropomyosin-binding subunit of the troponin complex and plays an essential role in the regulation of striated muscle contraction. In humans, mutations in this gene are associated with nemaline myopathy type 5. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:4504570-4516382
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000071798 ENSMUSP00000071704
ENSMUST00000086502
ENSMUST00000108587 ENSMUSP00000104228
ENSMUST00000163710 ENSMUSP00000129626
ENSMUST00000166161 ENSMUSP00000125795
ENSMUST00000168111
ENSMUST00000166268 ENSMUSP00000128476
ENSMUST00000169571
ENSMUST00000166959 ENSMUSP00000129109
ENSMUST00000163538 ENSMUSP00000127964
ENSMUST00000163722 ENSMUSP00000129409
ENSMUST00000163560 ENSMUSP00000132012
ENSMUST00000178163 ENSMUSP00000137198
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005523 tropomyosin binding
GO:0031014 troponin T binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0006937 regulation of muscle contraction
GO:0031444 slow-twitch skeletal muscle fiber contraction
GO:0045932 negative regulation of muscle contraction
Cellular Component
GO:0005861 troponin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Striated Muscle Contraction pathway
Muscle contraction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Striated Muscle Contraction pathway
Muscle contraction pathway
Muscle contraction pathway
Striated Muscle Contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001277903 NM_001277904 NM_011618 XM_006539720 XM_006539721 XM_006539726
OMIM
CCDS CCDS51973 CCDS71879 CCDS71880
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas