InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptprn

Summary

InnateDB Protein

IDBP-170583.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptprn

Protein Name

protein tyrosine phosphatase, receptor type, N

Synonyms

IA-2; mIA-A; mKIAA4064;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027404

InnateDB Gene

IDBG-170581 (Ptprn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity
GO:0030507	spectrin binding
GO:0051020	GTPase binding

Biological Process

GO:0000302	response to reactive oxygen species
GO:0006470	protein dephosphorylation
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0009749	response to glucose
GO:0016311	dephosphorylation
GO:0019221	cytokine-mediated signaling pathway
GO:0032868	response to insulin
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0043627	response to estrogen
GO:0051591	response to cAMP

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:102765

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR021613 Protein-tyrosine phosphatase receptor IA-2 ectodomain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF11548

PRINTS

PR00700

PIRSF

SMART

SM00194
SM00404

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt