Version 5.4
Interaction: BIRC6 :: DIABLO XML
Summary
InnateDB Group ID 174760
Short name BIRC6 :: DIABLO
Full name BIRC6 physically interacts with DIABLO
Interaction type physical interaction
Participants
Participant 1
Molecule: IDBG-43545
Molecule type: protein
Species: Homo sapiens
HUGO: BIRC6
Full name: baculoviral IAP repeat containing 6
Direction: input
Biological role: enzyme target,unspecified,unspecified role
Participant 2
Molecule: IDBG-62263
Molecule type: protein
Species: Homo sapiens
HUGO: DIABLO
Full name: diablo, IAP-binding mitochondrial protein
Direction: input
Biological role: enzyme,unspecified,unspecified role
Evidence Reference 1
InnateDB ID IDB-114407.2
Last Modified 2010-03-07
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB
Source database ID IDB-114407
PMID 15300255
Interaction detection method anti tag coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line 293T
Cell type
Tissue type kidney cell line
Comment Tags: Myc-BIRC6; interacting domain: N-terminal of mature DIABLO bind to N-terminus BIR (aa 1-1648) BIRC6
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 bait
2) DIABLO prey
Evidence Reference 2
InnateDB ID IDB-114449.2
Last Modified 2010-03-07
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB
Source database ID IDB-114449
PMID 15200957
Interaction detection method coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line 293T
Cell type
Tissue type kidney cell line
Comment Mutant met-DIABLO (aa1-55) abolished interaction, showing importance of N-terminal tetrapeptide sequence. Interacting domain: N-terminal tetrapeptide sequences DIABLO interacting with BIR domain of BIRC6
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 bait
2) DIABLO mass spectrometry prey
Evidence Reference 3
InnateDB ID IDB-252926.1
Last Modified 2012-02-14
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-555923
PMID 15300255
Interaction detection method enzymatic study
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 predetermined participant bait NP_057336
2) DIABLO predetermined participant prey 56616
Evidence Reference 4
InnateDB ID IDB-972374.1
Last Modified 2013-07-09
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-696737
PMID 15507451
Interaction detection method pull down
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 predetermined participant bait NP_057336
2) DIABLO predetermined participant prey 56616
Evidence Reference 5
InnateDB ID IDB-1020131.1
Last Modified 2013-07-09
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-677884
PMID 15200957
Interaction detection method enzymatic study
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 predetermined participant bait NP_057336
2) DIABLO predetermined participant prey 56616
Evidence Reference 6
InnateDB ID IDB-1730718.1
Last Modified 2014-11-29
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIND
Source database ID 151045
PMID 15300255
Interaction detection method coimmunoprecipitation
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 unspecified role NP_057336
2) DIABLO unspecified role NP_063940
Evidence Reference 7
InnateDB ID IDB-1730983.1
Last Modified 2014-11-29
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIND
Source database ID 180585
PMID 15200957
Interaction detection method coimmunoprecipitation
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) BIRC6 bait NP_057336
2) DIABLO prey NP_063940

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca