Version 5.4
Mus musculus Gene: Git1
Summary
InnateDB Gene IDBG-201554.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Git1
Gene Name G protein-coupled receptor kinase-interactor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000011877
Encoded Proteins
IDBP-201556
G protein-coupled receptor kinase-interactor 1
IDBP-201558
G protein-coupled receptor kinase-interactor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108262:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:77493562-77507786
Strand Forward strand
Band B5
Transcripts
ENSMUST00000037285 ENSMUSP00000037210
ENSMUST00000100812 ENSMUSP00000098375
ENSMUST00000152428
ENSMUST00000127302
ENSMUST00000139410
ENSMUST00000128796
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 53 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0016235 aggresome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108262
View Gene Order
ENSBTAG00000012040
Not yet available
Pathways
NETPATH
REACTOME
REACT_258158
EPH-Ephrin signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_241951
Ephrin signaling pathway
KEGG
mmu04810
Regulation of actin cytoskeleton pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_228226
Ephrin signaling pathway
REACT_228170
EPH-Ephrin signaling pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa05120
Epithelial cell signaling in Helicobacter pylori infection pathway
hsa04144
Endocytosis pathway
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
cdc42_reg_pathway
Regulation of CDC42 activity
integrin_a4b1_pathway
Alpha4 beta1 integrin signaling events
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.290182
RefSeq NM_001004144 XM_006532949
OMIM
CCDS CCDS25080
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca