InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: APLNR

Summary

InnateDB Protein

IDBP-811512.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APLNR

Protein Name

apelin receptor

Synonyms

AGTRL1; APJ; APJR; HG11;

Species

Homo sapiens

Ensembl Protein

ENSP00000475344

InnateDB Gene

IDBG-46271 (APLNR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007369	gastrulation
GO:0007507	heart development
GO:0050878	regulation of body fluid levels
GO:0050909	sensory perception of taste

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR003904 APJ receptor
IPR007960 Mammalian taste receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019426 7TM GPCR, serpentine receptor class v (Srv)

PFAM

PF00001
PF05296
PF10323

PRINTS

PR00241
PR00237
PR01416

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P35414