Version 5.4
Homo sapiens Protein: CLEC4M
Summary
InnateDB Protein IDBP-765541.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC4M
Protein Name
Synonyms CD209L; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN;
Species Homo sapiens
Ensembl Protein ENSP00000470132
InnateDB Gene IDBG-23635 (CLEC4M)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
GO:0030369 ICAM-3 receptor activity
GO:0042605 peptide antigen binding
GO:0046790 virion binding
GO:0046872 metal ion binding
Biological Process
GO:0006897 endocytosis
GO:0007159 leukocyte cell-cell adhesion
GO:0009988 cell-cell recognition
GO:0010468 regulation of gene expression
GO:0019048 modulation by virus of host morphology or physiology
GO:0019062 virion attachment to host cell
GO:0019079 viral genome replication
GO:0019882 antigen processing and presentation
GO:0030193 regulation of blood coagulation
GO:0035556 intracellular signal transduction
GO:0045087 innate immune response
GO:0046968 peptide antigen transport
GO:0075733 intracellular transport of virus
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H2X3
PhosphoSite PhosphoSite-Q9H2X3
TrEMBL
UniProt Splice Variant
Entrez Gene 10332
UniGene Hs.613731
RefSeq NP_001138378
HUGO HGNC:13523
OMIM 605872
CCDS CCDS59347
HPRD 12060
IMGT
EMBL AB015629 AC008812 AF209480 AF209481 AF245219 AF290887 AK023750 AK292278 AY042234 AY042235 AY042236 AY042237 AY042238 AY042239 AY042240 AY343913 BC038851
GenPept AAG13815 AAG13848 AAH38851 AAK20998 AAK91859 AAK91860 AAK91861 AAK91862 AAK91863 AAK91864 AAK91865 AAR04559 BAA76496 BAB14667 BAF84967

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca