InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ND3

Summary

InnateDB Protein

IDBP-701832.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ND3

Protein Name

NADH-ubiquinone oxidoreductase chain 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053159

InnateDB Gene

IDBG-649166 (ND3)

Protein Structure

UniProt Annotation

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Localization

Mitochondrion membrane {ECO:0000269PubMed:17060615}; Multi-pass membrane protein {ECO:0000269PubMed:17060615}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0016491	oxidoreductase activity

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005747	mitochondrial respiratory chain complex I
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane
GO:0070469	respiratory chain

Protein Structure and Domains

PDB ID

InterPro

IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3

PFAM

PF00507

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB074962 AB074963 AB074964 AB074965 AB074966 AB074967 AB074968 AF490528 AF490529 AF492351 AF493541 AF493542 AY308066 AY308067 AY308068 AY308069 AY526085 AY676855 AY676856 AY676857 AY676858 AY676859 AY676860 AY676861 AY676862 AY676863 AY676864 AY676865 AY676866 AY676867 AY676868 AY676869 AY676870 AY676871 AY676872 AY676873 DQ124371 DQ124372 DQ124373 DQ124374 DQ124375 DQ124376 DQ124377 DQ124378 DQ124379 DQ124380 DQ124381 DQ124382 DQ124383 DQ124384 DQ124385 DQ124386 DQ124387 DQ124388 DQ124389 DQ124390 DQ124391 DQ124392 DQ124393 DQ124394 DQ124395 DQ124396 DQ124397 DQ124398 DQ124399 DQ124400 DQ124401 DQ124402 DQ124404 DQ124405 DQ124406 DQ124407 DQ124408 DQ124409 DQ124410 DQ124411 DQ124412 DQ124413 DQ124414 DQ124415 DQ124416 DQ124417 DQ124418 EU177815 EU177816 EU177817 EU177818 EU177819 EU177820 EU177821 EU177822 EU177823 EU177824 EU177825 EU177826 EU177827 EU177828 EU177829 EU177830 EU177831 EU177832 EU177833 EU177834 EU177835 EU177836 EU177837 EU177838 EU177839 EU177840 EU177841 EU177842 EU177843 EU177844 EU177845 EU177846 EU177847 EU177848 EU177849 EU177850 EU177851 EU177852 EU177853 EU177854 EU177855 EU177856 EU177857 EU177858 EU177859 EU177860 EU177861 EU177862 EU177863 EU177864 EU177865 EU177866 EU177867 FJ971080 FJ971081 FJ971082 FJ971083 FJ971084 FJ971085 FJ971086 FJ971087 GQ129207 GQ129208 GU947007 GU947008 GU947009 GU947010 GU947011 GU947012 GU947013 GU947014 GU947015 GU947016 GU947017 GU947018 GU947019 GU947020 GU947021 HM045018 HQ025805 HQ184030 HQ184031 HQ184032 HQ184033 HQ184034 HQ184035 HQ184036 HQ184037 HQ184038 HQ184039 HQ184040 HQ184041 HQ184042 HQ184043 HQ184044 HQ184045 JN817300 JN817301 JN817306 JN817307 JN817308 JN817309 JN817310 JN817311 JN817312 JN817313 JN817315 JN817316 JN817317 JN817318 JN817319 JN817320 JN817321 JN817322 JN817323 JN817324 JN817325 JN817326 JN817327 JN817328 JN817329 JN817332 JN817333 JN817334 JN817335 JN817336 JN817337 JN817338 JN817339 JN817340 JN817341 JN817342 JN817343 JN817344 JN817345 JN817346 JN817347 JN817348 JN817349 JN817350 JN817351 JQ967333 KC153972 KC153973 KC153974 KC153975 KC153976 KC153977 KF163061 KF163062 KF163063 KF163064 KF163065 KF163066 KF163067 KF163068 KF163069 KF163070 KF163071 KF163072 KF163073 KF163074 KF163075 KF163076 KF163077 KF163078 KF163079 KF163080 KF163081 KF163082 KF163083 KF163084 KF163085 KF163086 KF163087 KF163088 KF163089 KF163090 KF163091 KF163092 KF163093 KF163094 KF926377 V00654

GenPept

AAM08324 AAM08337 AAM12796 AAM12809 AAP47835 AAP47848 AAP47861 AAP47874 AAQ06600 AAS18249 AAV88117 AAV88130 AAV88143 AAV88156 AAV88169 AAV88182 AAV88195 AAV88208 AAV88221 AAV88234 AAV88247 AAV88260 AAV88273 AAV88286 AAV88299 AAV88312 AAV88325 AAV88338 AAV88351 AAZ16527 AAZ16540 AAZ16553 AAZ16566 AAZ16579 AAZ16592 AAZ16605 AAZ16618 AAZ16631 AAZ16644 AAZ16657 AAZ16670 AAZ16683 AAZ16696 AAZ16709 AAZ16722 AAZ16735 AAZ16748 AAZ16761 AAZ16774 AAZ16787 AAZ16800 AAZ16813 AAZ16826 AAZ16839 AAZ16852 AAZ16865 AAZ16878 AAZ16891 AAZ16904 AAZ16917 AAZ16930 AAZ16956 AAZ16969 AAZ16982 AAZ16995 AAZ17008 AAZ17021 AAZ17034 AAZ17047 AAZ17060 AAZ17073 AAZ17086 AAZ17099 AAZ17112 AAZ17125 AAZ17138 ABV70212 ABV70225 ABV70238 ABV70251 ABV70264 ABV70277 ABV70290 ABV70303 ABV70316 ABV70329 ABV70342 ABV70355 ABV70368 ABV70381 ABV70394 ABV70407 ABV70420 ABV70433 ABV70446 ABV70459 ABV70472 ABV70485 ABV70498 ABV70511 ABV70524 ABV70537 ABV70550 ABV70563 ABV70576 ABV70589 ABV70602 ABV70615 ABV70628 ABV70641 ABV70654 ABV70667 ABV70680 ABV70693 ABV70706 ABV70719 ABV70732 ABV70745 ABV70758 ABV70771 ABV70784 ABV70797 ABV70810 ABV70823 ABV70836 ABV70849 ABV70862 ABV70875 ABV70888 ACQ73756 ACQ73769 ACQ73782 ACQ73795 ACQ73808 ACQ73821 ACQ73834 ACQ73847 ACR19414 ACR19427 ADF29604 ADF49334 ADF49347 ADF49360 ADF49373 ADF49386 ADF49399 ADF49412 ADF49425 ADF49438 ADF49451 ADF49464 ADF49477 ADF49490 ADF49503 ADF49516 ADM35742 ADN11782 ADN11795 ADN11808 ADN11821 ADN11834 ADN11847 ADN11860 ADN11873 ADN11886 ADN11899 ADN11912 ADN11925 ADN11938 ADN11951 ADN11964 ADN11977 AER53681 AER53694 AER53759 AER53772 AER53785 AER53798 AER53811 AER53824 AER53837 AER53850 AER53876 AER53889 AER53902 AER53915 AER53928 AER53941 AER53954 AER53967 AER53980 AER53993 AER54006 AER54019 AER54032 AER54045 AER54058 AER54097 AER54110 AER54123 AER54136 AER54149 AER54162 AER54175 AER54188 AER54201 AER54214 AER54227 AER54240 AER54253 AER54266 AER54279 AER54292 AER54305 AER54318 AER54331 AER54344 AFK75891 AGB56905 AGB56918 AGB56931 AGB56944 AGB56957 AGB56970 AGU00425 AGU00438 AGU00451 AGU00464 AGU00477 AGU00490 AGU00503 AGU00516 AGU00529 AGU00542 AGU00555 AGU00568 AGU00581 AGU00594 AGU00607 AGU00620 AGU00633 AGU00646 AGU00659 AGU00672 AGU00685 AGU00698 AGU00711 AGU00724 AGU00737 AGU00750 AGU00763 AGU00776 AGU00789 AGU00802 AGU00815 AGU00828 AGU00841 AGU00854 AHI51992 BAC54742 BAC54755 BAC54768 BAC54781 BAC54794 BAC54807 BAC54820 CAA24008

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca