InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: C3AR1

Summary

InnateDB Protein

IDBP-691998.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

C3AR1

Protein Name

C3a anaphylatoxin chemotactic receptor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026308

InnateDB Gene

IDBG-639813 (C3AR1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004942	anaphylatoxin receptor activity
GO:0004943	C3a anaphylatoxin receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0010759	positive regulation of macrophage chemotaxis
GO:0045766	positive regulation of angiogenesis
GO:0090023	positive regulation of neutrophil chemotaxis

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001274 C5a1/C5a2 anaphylatoxin chemotactic receptor
IPR001644 C3a anaphylatoxin chemotactic receptor
IPR002234 Anaphylatoxin chemotactic receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00426
PR01060
PR01104

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite