Version 5.4
Bos taurus Protein: PRG4
Summary
InnateDB Protein IDBP-689594.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRG4
Protein Name proteoglycan 4
Synonyms lubricin; MSF;
Species Bos taurus
Ensembl Protein ENSBTAP00000015839
InnateDB Gene IDBG-637552 (PRG4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0030247 polysaccharide binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0042127 regulation of cell proliferation
GO:0045409 negative regulation of interleukin-6 biosynthetic process
GO:0071425 hematopoietic stem cell proliferation
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR000585 Hemopexin-like domain
IPR001212 Somatomedin B domain
IPR018487 Hemopexin-like repeats
IPR020436 Somatomedin B, chordata
PFAM PF01033
PF00045
PRINTS PR00022
PIRSF
SMART SM00201
SM00120
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MDS0
UniProt Splice Variant
Entrez Gene 280867
UniGene
RefSeq NP_001193562
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043627
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca