Version 5.4
Bos taurus Protein: UOX
Summary
InnateDB Protein IDBP-689420.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UOX
Protein Name Uricase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000033405
InnateDB Gene IDBG-637414 (UOX)
Protein Structure
UniProt Annotation
Function Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin. {ECO:0000250}.
Subcellular Localization Peroxisome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004846 urate oxidase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0019628 urate catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
Protein Structure and Domains
PDB ID
InterPro IPR002042 Uricase
PFAM PF01014
PRINTS PR00093
PIRSF PIRSF000241
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHG7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 514113
UniGene Bt.25743
RefSeq NP_001069116
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105244
GenPept AAI05245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca