Version 5.4
Bos taurus Protein: BT.45038
Summary
InnateDB Protein IDBP-688253.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.45038
Protein Name oncostatin-M precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021515
InnateDB Gene IDBG-636338 (BT.45038)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005147 oncostatin-M receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0006955 immune response
GO:0007422 peripheral nervous system development
GO:0008284 positive regulation of cell proliferation
GO:0009408 response to heat
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0042503 tyrosine phosphorylation of Stat3 protein
GO:0042506 tyrosine phosphorylation of Stat5 protein
GO:0042508 tyrosine phosphorylation of Stat1 protein
GO:0043410 positive regulation of MAPK cascade
GO:0045835 negative regulation of meiosis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046888 negative regulation of hormone secretion
GO:0048266 behavioral response to pain
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005900 oncostatin-M receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR001581 Leukemia inhibitory factor /oncostatin
IPR009079 Four-helical cytokine-like, core
PFAM PF01291
PRINTS
PIRSF
SMART SM00080
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N366
UniProt Splice Variant
Entrez Gene 319086
UniGene Bt.45038
RefSeq NP_783644
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045615
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca