InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ELMOD3

Summary

InnateDB Protein

IDBP-687039.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELMOD3

Protein Name

ELMO domain-containing protein 3

Synonyms

RBED1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000049817

InnateDB Gene

IDBG-635193 (ELMOD3)

Protein Structure

UniProt Annotation

Function

Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity. {ECO:0000250}.

Subcellular Localization

Cell projection, stereocilium {ECO:0000250}. Cell projection, kinocilium {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Also present in the cuticular plate of auditory hair cells. Expressed along the length of the stereocilia, but excluded from the very tip. Colocalizes with F- actin cytoskeleton (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006909

phagocytosis

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005929	cilium
GO:0032420	stereocilium
GO:0042995	cell projection
GO:0060091	kinocilium

Protein Structure and Domains

PDB ID

InterPro

IPR006816 Engulfment/cell motility, ELMO

PFAM

PF04727

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58DT5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

535421

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BT021512 BT021901 BT026263

GenPept

AAX46359 AAX46748 ABG67102