Bos taurus Protein: AMD1
Summary
InnateDB Protein IDBP-683065.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMD1
Protein Name S-adenosylmethionine decarboxylase proenzymeS-adenosylmethionine decarboxylase alpha chainS-adenosylmethionine decarboxylase beta chain
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004338
InnateDB Gene IDBG-631521 (AMD1)
Protein Structure
UniProt Annotation
Function Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004014 adenosylmethionine decarboxylase activity
GO:0016829 lyase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006557 S-adenosylmethioninamine biosynthetic process
GO:0006596 polyamine biosynthetic process
GO:0006597 spermine biosynthetic process
GO:0008295 spermidine biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001985 S-adenosylmethionine decarboxylase
IPR016067 S-adenosylmethionine decarboxylase, core
IPR018167 S-adenosylmethionine decarboxylase subgroup
PFAM PF01536
PRINTS
PIRSF PIRSF001355
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50243
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280997
UniGene Bt.87633
RefSeq NP_776415
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123795 M14289 M95605
GenPept AAA30359 AAA30360 AAI23796