Version 5.4
Homo sapiens Protein: MARCH10
Summary
InnateDB Protein IDBP-63106.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARCH10
Protein Name membrane-associated ring finger (C3HC4) 10
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000311496
InnateDB Gene IDBG-63104 (MARCH10)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000305}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011016 Zinc finger, RING-CH-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF12906
PF00097
PRINTS
PIRSF
SMART SM00744
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NA82
PhosphoSite PhosphoSite-Q8NA82
TrEMBL J3KTK3
UniProt Splice Variant
Entrez Gene 162333
UniGene Hs.710548
RefSeq NP_689811
HUGO HGNC:26655
OMIM 613337
CCDS CCDS11635
HPRD 08762
IMGT
EMBL AC005821 AC068512 AC080038 AK093076 AK097506 BC035021 CH471109
GenPept AAH35021 BAC04044 BAC05079 EAW94337 EAW94338

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca