InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp13a3

Summary

InnateDB Protein

IDBP-621557.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp13a3

Protein Name

ATPase type 13A3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128224

InnateDB Gene

IDBG-152011 (Atp13a3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expression is greatest in liver, followed by kidney, colon, stomach, brain and small intestine. Isoform 1 is highly expressed in the kidney while isoform 2 is highly expressed in the brain. {ECO:0000269PubMed:15381061}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003674	molecular_function
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006812	cation transport

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2685387

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR004014 Cation-transporting P-type ATPase, N-terminal
IPR006544 Cation-transporting P-type ATPase, subfamily V
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00690
PF12409
PF00122
PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

SM00831

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt