InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SPG11

Summary

InnateDB Protein

IDBP-602525.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPG11

Protein Name

spastic paraplegia 11 (autosomal recessive)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000445278

InnateDB Gene

IDBG-9834 (SPG11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008219

cell death

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005765	lysosomal membrane
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0031410	cytoplasmic vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96JI7

PhosphoSite

PhosphoSite-Q96JI7

TrEMBL

H0YN96

UniProt Splice Variant

Entrez Gene

80208

UniGene

Hs.667399

RefSeq

NP_001153699

HUGO

HGNC:11226

OMIM

610844

CCDS

CCDS53939

HPRD

07963

IMGT

EMBL

AB058743 AB470309 AC009996 AK025092 AK091176 AL834168 AY954502 BC024161 BC067798 BC094704 BC150640 BC153879

GenPept

AAH24161 AAH67798 AAH94704 AAI50641 AAI53880 AAX54692 BAB15065 BAB47469 BAC03600 BAH58759 CAH10686