Version 5.4
Homo sapiens Protein: CD177
Summary
InnateDB Protein IDBP-55105.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD177
Protein Name CD177 molecule
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367251
InnateDB Gene IDBG-55103 (CD177)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000269PubMed:12239154}; Lipid-anchor, GPI-anchor {ECO:0000269PubMed:12239154}.
Disease Associations
Tissue Specificity Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET). {ECO:0000269PubMed:10753836, ECO:0000269PubMed:12377969}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007596 blood coagulation
GO:0050900 leukocyte migration
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N6Q3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 57126
UniGene
RefSeq
HUGO HGNC:30072
OMIM 162860
CCDS
HPRD 01222
IMGT
EMBL AF146747 AJ290452 AJ305326 AJ310433 AY358932 BC029167 BT020111
GenPept AAG00895 AAH29167 AAQ89291 AAV38914 CAC44459 CAC83724 CAC83758

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca