Version 5.4
| Homo sapiens Protein: VWCE | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-49888.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | VWCE | ||||||
| Protein Name | von Willebrand factor C and EGF domains | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Protein | ENSP00000334186 | ||||||
| InnateDB Gene | IDBG-49886 (VWCE) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma. {ECO:0000269PubMed:16496348}. | ||||||
| Subcellular Localization | Secreted {ECO:0000305}. Note=According to PubMed:16496348 is localized in the cytoplasm. {ECO:0000269PubMed:16496348}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expressed in liver. {ECO:0000269PubMed:16496348}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | |||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001007 von Willebrand factor, type C IPR001881 EGF-like calcium-binding domain IPR006552 VWC out |
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| PFAM |
PF00008
PF00093 PF07645 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00181
SM00214 SM00179 SM00215 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q96DN2 | ||||||
| PhosphoSite | PhosphoSite-Q96DN2 | ||||||
| TrEMBL | B4DY31 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 220001 | ||||||
| UniGene | Hs.60640 | ||||||
| RefSeq | NP_689931 | ||||||
| HUGO | HGNC:26487 | ||||||
| OMIM | 611115 | ||||||
| CCDS | CCDS8002 | ||||||
| HPRD | 08116 | ||||||
| IMGT | |||||||
| EMBL | AK056571 AK302241 AP003037 AY205235 BC052564 BC077719 BC142624 CH471076 | ||||||
| GenPept | AAI42625 AAO47606 BAB71219 BAG63593 EAW73932 | ||||||