Version 5.4
Homo sapiens Protein: GFRA2
Summary
InnateDB Protein IDBP-483838.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GFRA2
Protein Name GDNF family receptor alpha 2
Synonyms GDNFRB; NRTNR-ALPHA; NTNRA; RETL2; TRNR2;
Species Homo sapiens
Ensembl Protein ENSP00000429979
InnateDB Gene IDBG-9892 (GFRA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0019898 extrinsic component of membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003438 Glial cell line-derived neurotrophic factor receptor
IPR003504 Glial cell line-derived neurotrophic factor receptor alpha 2
IPR016017 GDNF/GAS1
PFAM PF02351
PRINTS PR01316
PR01318
PIRSF
SMART SM00907
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00451
PhosphoSite PhosphoSite-O00451
TrEMBL
UniProt Splice Variant
Entrez Gene 2675
UniGene Hs.720276
RefSeq NP_001158510
HUGO HGNC:4244
OMIM 601956
CCDS
HPRD 11801
IMGT
EMBL AC105186 AC129925 AF002700 AP008236 AY326396 AY941828 BC041688 U93703 U97145
GenPept AAB61922 AAC51647 AAC52036 AAH41688 AAP88378 AAX46325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca