InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COL6A3

Summary

InnateDB Protein

IDBP-479189.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COL6A3

Protein Name

collagen, type VI, alpha 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000418285

InnateDB Gene

IDBG-84192 (COL6A3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007411	axon guidance
GO:0007517	muscle organ development
GO:0010951	negative regulation of endopeptidase activity
GO:0022617	extracellular matrix disassembly
GO:0030198	extracellular matrix organization
GO:0030574	collagen catabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005589	collagen type VI trimer
GO:0005615	extracellular space
GO:0005788	endoplasmic reticulum lumen
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002035 von Willebrand factor, type A
IPR002223 Proteinase inhibitor I2, Kunitz metazoa
IPR003961 Fibronectin, type III
IPR008160 Collagen triple helix repeat

PFAM

PF00092
PF00014
PF00041
PF01108
PF01391

PRINTS

PR00759

PIRSF

SMART

SM00327
SM00131
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt