InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adcy9

Summary

InnateDB Protein

IDBP-401744.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adcy9

Protein Name

adenylate cyclase 9

Synonyms

ACtp10; AW125421; D16Wsu65e; mKIAA0520;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113498

InnateDB Gene

IDBG-129643 (Adcy9)

Protein Structure

UniProt Annotation

Function

May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Found in decreasing order in skeletal muscle, heart, adrenal gland, ovary and brain; and to a lesser extent, in kidney, liver, testis, lung, thymus and spleen.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004016	adenylate cyclase activity
GO:0005524	ATP binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0046872	metal ion binding

Biological Process

GO:0006171	cAMP biosynthetic process
GO:0007190	activation of adenylate cyclase activity
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction