Version 5.4
Homo sapiens Protein: THPO
Summary
InnateDB Protein IDBP-386170.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THPO
Protein Name thrombopoietin
Synonyms MGDF; MKCSF; ML; MPLLG; THCYT1; TPO;
Species Homo sapiens
Ensembl Protein ENSP00000411704
InnateDB Gene IDBG-68171 (THPO)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005179 hormone activity
Biological Process
GO:0008283 cell proliferation
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001323 Erythropoietin/thrombopoeitin
IPR003978 Thrombopoeitin
IPR009079 Four-helical cytokine-like, core
PFAM PF00758
PRINTS PR01485
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL O94784
UniProt Splice Variant
Entrez Gene 7066
UniGene Hs.734657
RefSeq NP_001276956
HUGO HGNC:11795
OMIM 600044
CCDS
HPRD 02500
IMGT
EMBL AB014682 AC078797
GenPept BAA34931

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca