InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PNPLA8

Summary

InnateDB Protein

IDBP-385201.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PNPLA8

Protein Name

patatin-like phospholipase domain containing 8

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000394988

InnateDB Gene

IDBG-36334 (PNPLA8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004622	lysophospholipase activity
GO:0005488	binding
GO:0005524	ATP binding
GO:0047499	calcium-independent phospholipase A2 activity

Biological Process

GO:0001516	prostaglandin biosynthetic process
GO:0006629	lipid metabolic process
GO:0006631	fatty acid metabolic process
GO:0006644	phospholipid metabolic process
GO:0008152	metabolic process
GO:0008219	cell death
GO:0019369	arachidonic acid metabolic process
GO:0034638	phosphatidylcholine catabolic process
GO:0036151	phosphatidylcholine acyl-chain remodeling
GO:0036152	phosphatidylethanolamine acyl-chain remodeling
GO:0043651	linoleic acid metabolic process
GO:0044281	small molecule metabolic process
GO:0046338	phosphatidylethanolamine catabolic process
GO:0046474	glycerophospholipid biosynthetic process
GO:0050482	arachidonic acid secretion

Cellular Component

GO:0000139	Golgi membrane
GO:0005622	intracellular
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0048471	perinuclear region of cytoplasm