InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PNPLA6

Summary

InnateDB Protein

IDBP-368380.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PNPLA6

Protein Name

patatin-like phospholipase domain containing 6

Synonyms

BNHS; iPLA2delta; NTE; NTEMND; SPG39; sws;

Species

Homo sapiens

Ensembl Protein

ENSP00000407509

InnateDB Gene

IDBG-22916 (PNPLA6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004622	lysophospholipase activity

Biological Process

GO:0001525	angiogenesis
GO:0006629	lipid metabolic process
GO:0008152	metabolic process
GO:0008219	cell death
GO:0009887	organ morphogenesis
GO:0016042	lipid catabolic process
GO:0046470	phosphatidylcholine metabolic process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000595 Cyclic nucleotide-binding domain
IPR002641 Patatin/Phospholipase A2-related
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF00027
PF01734

PRINTS

PIRSF

SMART

SM00100

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8IY17