Version 5.4
Homo sapiens Protein: SLC5A6
Summary
InnateDB Protein IDBP-294574.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A6
Protein Name solute carrier family 5 (sodium-dependent vitamin transporter), member 6
Synonyms SMVT;
Species Homo sapiens
Ensembl Protein ENSP00000384853
InnateDB Gene IDBG-37411 (SLC5A6)
Protein Structure
UniProt Annotation
Function Transports pantothenate, biotin and lipoate in the presence of sodium.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0006768 biotin metabolic process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0015939 pantothenate metabolic process
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001734 Sodium/solute symporter
IPR019900 Sodium/solute symporter, subgroup
PFAM PF00474
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y289
PhosphoSite PhosphoSite-Q9Y289
TrEMBL Q9HD19
UniProt Splice Variant
Entrez Gene 8884
UniGene Hs.435735
RefSeq XP_006712194
HUGO HGNC:11041
OMIM 604024
CCDS CCDS1740
HPRD 04934
IMGT
EMBL AC013403 AF069307 AF081571 AF116241 AF288781 AF442149 AF442150 AK314545 BC012806 BC015631 CH471053
GenPept AAD31727 AAD37481 AAD37502 AAG00587 AAH12806 AAH15631 AAL84706 AAL84707 AAX93172 BAG37132 EAX00620 EAX00621 EAX00622

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca