Version 5.4
| Mus musculus Protein: Arhgef9 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-252946.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Arhgef9 | ||||||||
| Protein Name | CDC42 guanine nucleotide exchange factor (GEF) 9 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000109508 | ||||||||
| InnateDB Gene | IDBG-160486 (Arhgef9) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Detected in embryonic and adult brain. {ECO:0000269PubMed:11168555}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2442233 | ||||||||
| InterPro |
IPR000219
Dbl homology (DH) domain IPR001452 SH3 domain IPR001849 Pleckstrin homology domain IPR011511 Variant SH3 domain |
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| PFAM |
PF00621
PF00018 PF14604 PF00169 PF07653 |
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| PRINTS |
PR00452
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| PIRSF | |||||||||
| SMART |
SM00325
SM00326 SM00233 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3UTH8 | ||||||||
| PhosphoSite | PhosphoSite-Q3UTH8 | ||||||||
| TrEMBL | S4R1A7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 236915 | ||||||||
| UniGene | Mm.44841 | ||||||||
| RefSeq | XP_006528055 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Arhgef9 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS72409 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK038840 AK122280 AK139416 AK163874 AL807821 BC141385 BX470092 | ||||||||
| GenPept | AAI41386 BAC30147 BAC65562 BAE24002 BAE37525 CAM18133 CAM18135 CAM19851 CAM19853 | ||||||||