Version 5.4
Mus musculus Protein: Ckap2l
Summary
InnateDB Protein IDBP-205881.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ckap2l
Protein Name cytoskeleton associated protein 2-like
Synonyms 2010016H04Rik; 2610318C08Rik; AV070319; radmis; rdm;
Species Mus musculus
Ensembl Protein ENSMUSP00000056145
InnateDB Gene IDBG-205879 (Ckap2l)
Protein Structure
UniProt Annotation
Function Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells. {ECO:0000269PubMed:24260314}.
Subcellular Localization Cytoplasm, cytoskeleton, spindle pole {ECO:0000269PubMed:24260314}. Note=Uniformly distributed along each microtubule bundle of spindles in addition to centrioles during mitosis, expression promptly diminishes at interphase.
Disease Associations
Tissue Specificity Highly expressed in regions of active neurogenesis and neural stem/progenitor cells (NSPCs), both embryonic and adult, not detected in lung, liver, kidney, heart, and skeletal muscle. {ECO:0000269PubMed:24260314}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
Protein Structure and Domains
PDB ID MGI:1917716
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TS74
PhosphoSite PhosphoSite-Q7TS74
TrEMBL
UniProt Splice Variant
Entrez Gene 70466
UniGene Mm.45785
RefSeq NP_853620
MGI ID
MGI Symbol Ckap2l
OMIM
CCDS CCDS16724
HPRD
IMGT
EMBL AB455263 AK153766 AL772347 BC032969 BC053443
GenPept AAH32969 AAH53443 BAE32177 BAO05265 CAM15803

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca