Version 5.4
Mus musculus Protein: Dnajb14
Summary
InnateDB Protein IDBP-196019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajb14
Protein Name DnaJ (Hsp40) homolog, subfamily B, member 14
Synonyms 5730496F10Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000087641
InnateDB Gene IDBG-196047 (Dnajb14)
Protein Structure
UniProt Annotation
Function Acts as a co-chaperone with HSPA8 and promotes the degradation of misfolded transmembrane proteins in the ER- associated degradation (ERAD) pathway. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1917854
InterPro IPR001623 DnaJ domain
IPR015399 Domain of unknown function DUF1977, DnaJ-like
PFAM PF00226
PF09320
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q149L6
PhosphoSite PhosphoSite-Q149L6
TrEMBL
UniProt Splice Variant
Entrez Gene 70604
UniGene Mm.418442
RefSeq NP_001028327
MGI ID
MGI Symbol Dnajb14
OMIM
CCDS CCDS51077
HPRD
IMGT
EMBL AK139489 AK160961 BC117717 BC117718
GenPept AAI17718 AAI17719 BAE24035 BAE36117

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca