Version 5.4
Mus musculus Protein: Slc16a4
Summary
InnateDB Protein IDBP-185151.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc16a4
Protein Name solute carrier family 16 (monocarboxylic acid transporters), member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000029502
InnateDB Gene IDBG-185149 (Slc16a4)
Protein Structure
UniProt Annotation
Function Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0015293 symporter activity
Biological Process
GO:0008150 biological_process
GO:0055085 transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2385183
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R0M8
PhosphoSite PhosphoSite-Q8R0M8
TrEMBL
UniProt Splice Variant
Entrez Gene 229699
UniGene
RefSeq NP_666248
MGI ID
MGI Symbol Slc16a4
OMIM
CCDS CCDS17736
HPRD
IMGT
EMBL AC132405 AK045797 AK049873 AK052779 AK085492 AK136837 BC025441 BC026596 CH466607
GenPept AAH25441 AAH26596 BAC32495 BAC33967 BAC35143 BAC39456 BAE23142 EDL01900

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca