Version 5.4
Mus musculus Protein: Aqp6
Summary
InnateDB Protein IDBP-183487.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp6
Protein Name aquaporin 6
Synonyms AI790337;
Species Mus musculus
Ensembl Protein ENSMUSP00000023754
InnateDB Gene IDBG-183485 (Aqp6)
Protein Structure
UniProt Annotation
Function Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005253 anion channel activity
GO:0015112 nitrate transmembrane transporter activity
GO:0015250 water channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0015706 nitrate transport
GO:0042476 odontogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID MGI:1341204
InterPro IPR000425 Major intrinsic protein
IPR023254 Aquaporin 6
IPR023271 Aquaporin-like
PFAM PF00230
PRINTS PR00783
PR02018
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C4A0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 11831
UniGene Mm.202309
RefSeq NP_780296
MGI ID
MGI Symbol Aqp6
OMIM
CCDS CCDS27824
HPRD
IMGT
EMBL AK082699
GenPept BAC38576

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca