Version 5.4
Mus musculus Protein: Snx15
Summary
InnateDB Protein IDBP-134634.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Snx15
Protein Name sorting nexin 15
Synonyms 1500032B08Rik; E130013C21Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000025702
InnateDB Gene IDBG-134632 (Snx15)
Protein Structure
UniProt Annotation
Function May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID MGI:1916274
InterPro IPR001683 Phox homologous domain
IPR007330 MIT
PFAM PF00787
PF04212
PRINTS
PIRSF
SMART SM00312
SM00745
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91WE1
PhosphoSite PhosphoSite-Q91WE1
TrEMBL Q9CW22
UniProt Splice Variant
Entrez Gene 69024
UniGene Mm.329629
RefSeq NP_081188
MGI ID
MGI Symbol Snx15
OMIM
CCDS CCDS29495
HPRD
IMGT
EMBL AK005338 BC016091
GenPept AAH16091 BAB23960

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca