Version 5.4
Homo sapiens Protein: EDEM3
Summary
InnateDB Protein IDBP-105361.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EDEM3
Protein Name ER degradation enhancer, mannosidase alpha-like 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356482
InnateDB Gene IDBG-105359 (EDEM3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001382 Glycoside hydrolase, family 47
IPR003137 Protease-associated domain, PA
PFAM PF01532
PF02225
PRINTS PR00747
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q7L2Y5
UniProt Splice Variant
Entrez Gene 80267
UniGene Hs.604767
RefSeq
HUGO HGNC:16787
OMIM 610214
CCDS
HPRD 10724
IMGT
EMBL AL096819 BC016464 BC144149
GenPept AAH16464 AAI44150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca